Hardware wallets and paper wallets are the safest wallets. Trezor and Ledgers are among them. If you do not want to invest in buying an hardware wallet then you can use wallets like

Exodus:

Exodus is a desktop supported cryptocurrency wallet which deserves to be included in the bitcoin wallet list. Exodus supports nearly three dozen cryptocurrencies including Bitcoin, Litecoin, Dash, Zcash, Ethereum among the popular ones.

Electrum Wallet:

Electrum was mainly known for supporting Bitcoin and is widely considered to be a trusted software wallet in the bitcoin community. Electrum Wallet is a lightweight and easy platform to store your BTC holdings securely, where the bitcoin wallet sign up is convenient and easy.

Jaxx

Jaxx is becoming increasingly popular day by day as it provides a seamless user experience. Jaxx is available on different platforms like Windows, Linux and OS X desktops.