My thoughts are that tomorrow Sevilla could win against Barcelona. So odds for X2 = 2.50
Barca with the entire squad 100% fit might be too much for Sevilla. Also, Sevilla is Messi's favorite victim in La Liga (36 goals). I think BTTS and O2.5 might be the safest bet (a quick look at the recent h2h will tell you why it's safer).
That was a sure bet in the last couple of seasons, however I am bit concerned for today because Sevilla has started playing much better defense and Barca is still not firing on all cylinders. I still lean for both to score and over 2.5 but the stake will be low to medium instead of my max bet.