it really depends on the your profit taking appetite. people who want short term gains or require funds or people who earn small profits like to save as much as possible on the other hand for traders who trade a lot have a lot of experience and know they can recover whatever they lost are less concerned 'bout the fee.
No, I don't think that whales and big players never put concern with the fees. Of course, they will also as they want to gain more profit but are less considerate than those small players. As a matter of fact, everyone is looking for exchanges that could give them to the minimum that is why most reputable sites have to lower their fees for them to still gain the loyalty of their traders rather than to see them flew away because of the fees.
There is something we need to build between traders and exchange owners and that is reputation where we can fully trust this one as the listen and prioritize the needs of their clients rather than to looked their own benefits.