it really depends on the your profit taking appetite. people who want short term gains or require funds or people who earn small profits like to save as much as possible on the other hand for traders who trade a lot have a lot of experience and know they can recover whatever they lost are less concerned 'bout the fee.
Actually not regarding to the problem of cost in my opinion depends on each trader himself in responding to it. whether they object to the existence of a large trading fee or not. but indeed for traders with capital that is not so large, certainly have objections. but I personally for the average trade costs 0.25% -0.3% And that is not burdensome because our TP itself must also be bigger.
Maybe in addition to Fee trading there is another Fee that is shipping costs for bitcoin or altcoin. often times I see the exchange costs for shipping are also large. as in Hitbtc for fees there is quite large and burdensome