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Biggest DEX problems are
1. Lack of volume
2. Liquidity
3. Too low interest
4. Can be very annoying
Dex aren't showing good signs of interest yet but maybe in the future things can change drastically
Dex has no market makers since they are decentralized. Other centralized such as binance have a market makers to provide liquidity and volume to there exchange 24/7. Its impossible for a DEX to have a sustainable volume. Most probably. The majority of the volume of centralized exchange was fake so its not good to compared them to DEX.