I'm running dogecoin right now. Testing with 1 coin.
I added 7 miners to it, total of ~14Mhs of mining. Payouts are coming on average every 1 hour.
When I ran the pool with only 1 miner, memory was at 150MB. After adding 7 miners, memory is about 210MB.

http://s2.postimg.org/rnveu3sop/memoryscreen.png
image: http://postimg.org/image/kxexko5it/

Here is some additional information:
Latency ~ 0.01967s
DOA ~ 6.4%
Efficiency ~ 99.31%

Things are looking great!

I will be re-writing all of the charts graphs from https://github.com/hardcpp/P2PoolExtendedFrontEnd
I like what he has done, but I am taking it a step further.

Also, I will be modifying the p2pool source to include additional logging capabilities.

I have virtual machines running now with the same dogecoin pool. I did one, ran it, then did another to make sure I could repeat it. I also hardened some of the security, logins, passwords, and ports. I used Ubuntu Server 12.04. It has no desktop and is wicked fast! It boots up in about 2-3 seconds! Building in some redundancy and fail-over.