There are two big problems for me, but I can live with them:
-Missing Calendar
-Missing a Driver app (could be web), like outbox or google drive.
1. A decent ProtonMail alternative, Tutanota(also privacy focused), has a Calendar feature(not trying to steer you away from ProtonMail, both are very good services and I use both):
http://i.imgur.com/bAGAGoM.png2. I personally currently use Dropbox. Not a privacy-friendly alternative to Google Drive, but yea. Still looking for a better alternative that doesn't require me to sacrifice that much in terms of usability.
1. Last time i checked Tutanota, they still
planning to accept cryptocurrency. For user who have serious privacy concern, their only option is anonymous pre-load card.
2. There are many alternative such as :
* MegaSync. Gives you 50GB free storage and claim respect your privacy, but IMO it sounds to good to be true
* NextCloud. It's free and open source, but you need to run your own server.