... Some node will remove it from mempool because it is in block. But as it is "orphaned block", the transaction is invalidate.
as you said it,
"some", that means some other nodes still have it in their mempool
and they will keep broadcasting it until eventually it is dropped once it reaches max relay time limit
is it possible transaction is lost in bitcoin network?
in my understanding,
transaction lost isn't possible in bitcoin network (decentralised)
but transaction dropped from mempool is happening all the time for the reason nc50lc said
and when it's dropped, you can always re broadcast it again or create a new one with higher fee