how many daemons are you looking to run? HOST-32 seems a little overkill if all you are going to be doing is running the daemons. take a look at http://www.kimsufi.com/ it is run by the same people and provide much cheaper dedicated servers 
with regards to running a daemon, i assume you mean bitcoind? it should work/compile on any *nix/windows OS to be honest.. im only just getting to grips with the API myself so i cant help much there with the exception that if your going to access the API externally you need to make sure access is restricted to trusted IP addresses only... you dont want everyone attempting to access your API.
with regards to running a daemon, i assume you mean bitcoind? it should work/compile on any *nix/windows OS to be honest.. im only just getting to grips with the API myself so i cant help much there with the exception that if your going to access the API externally you need to make sure access is restricted to trusted IP addresses only... you dont want everyone attempting to access your API.