Absolutely, particularly when you are down to a few pieces left on the board and there aren't that many available moves. It could also be that a user could make several good-but-not-perfect moves, as dictated to by their computer software, to aid in avoiding being detected as cheating. Although the perfect set of moves will always win against a human, a good set of moves will still win almost all the time (certainly enough to turn a huge profit), while being significantly harder to detect.