IMO the best GUI would be browser-based
... Such solution would have a number of advantages.
Such as?
Such as:
- no need to install any huge packages/libraries/devenv in order to modify elements of the GUI
- easy to setup remote access to the GUI
- the ultimate platform independence (no wx, no other qt will ever give you that)
I can think of a lot of disadvantages, such as slower interface response times, exposing your interface to anyone who connects to a port, debugging it in all the browsers and their different versions, interfering browser plugins and adblocks, phishing, etc. The GUI is very simple, you won't get much advantage by using a browser as your GUI, it will probably be more difficult.
Slower response times don't matter in this kind of application.
You can limit the GUI to accept TCP connections only from localhost.
Developing and debugging of HTTP/JS apps is easy.
To give you an example, an idea, just have a look at the WebUI of uTorrent.
It is much more complex GUI that BitCoin will ever have. And it works really great, nobody has with it any problems you've mentioned. It works with basically every modern browser.