I think that we should build a confirmation honeypot so the community can get a better handle on how long you have to wait for a transaction to be effectively irreversible. If it turns out that it only really needs 1 minute rather than 1 hour, that could be a huge win for bitcoin adoption by bricks-and-mortar businesses.
More details on my blog
http://newmeraire.blogspot.com/2011/09/bitcoin-confirmation-honeypot.html.
What do you think?