ESports is a very wide-ranging issue, and if you want to bet on it then you should choose a game that you fully understand, I have some tips for you and this tip is the core part of what you need to know before you place your bets, when it comes to betting, you should always know what's better and what's the advantage, in eSports you'll never know who's going to win, MOBA games are one kind of game.
I do agree with that. Better bet on the game that you know of, not only familiar but by heart you know that specific game. Your chance of winning is even higher if you know both teams competing. Because if you are only familiar with specific esports game, you don't know the weaknesses and strengths of the teams involved, which will be your blind spot. So yes, the very simple trick in this game is to know what you are getting into.