Plenty of things can happen as a next big thing in crypto. My personal bets are:
1. Real dapps get their real adoption. Many people dont see it, cause such projects usually dont get much traction. But when they do, we can see SNX from 5 to 150mil in a couple months. And Im not talking about SNX here, cause its been mostly a pnd, but still a real adoption led to that pnd, not just worthless hype or news. There are plenty of projects, slowly developing and acquiring customers base. Still, they have almost zero traction in crypto world and almost never followed by crypto community. Why? Cause they spend their money developing their real business. And crypto related marketing usually brings unnecessary hype, followed by pnd. And real projects dont need that. Ask any CEO who want to really develop his business if he wants his stock to be pumped and dumped then. I believe no one tell you he wants that thing to happen. Instead hell want to have a steady business growth. Real customers. Real cash flowing into his business, by providing worthy services or goods. Tokens arent stocks. But for crypto projects its usually the only reflection of their inner value. So Im in such projects, whove built their solution during those 2 years since ICO, now slowly acquiring customers base who pays real money, generating revenue, which reflects in a slow tokens price growth, cause of buybacks and burns. Check such things as BCDT, VRA, VIDT and others with such approach. Buybacks/burns. Ready to use solution which can benefit real world. Paying customers. Licenses. I believe many, if dig deep in those will see how far we are now in terms of real adoption since 2017;
2. BTC massive adoption as store of value. Ive already said that and will say it again. As for its inner qualities, BTC right now is the best SOV in existence. Government currencies could replace cash. But those will never change gold or other SOVs. If one country decide to emit its own crypto cash, thats gonna be just its own national currency. But with more control over it from the government. Pretty similar to xrp, iota and other completely centralized coins. You should ask yourself, would you really use a coin, which can be completely eradicated from your account by lets say China, if youre US government? I seriously doubt it. Such currencies can really change cash on inner market. But those will never become a world currency or a new gold standard, cause theyd belong and gonna be controlled by a single entity. Completely opposite to BTC or gold, or most other SOVs;
3. Technological breakthroughs. Will we see ETH staying decentralized and have its current qualities with its new POS thing? Time will tell. But I believe if its gonna be the same old ETH, decentralized and secure, with 1-10k tps, that will bring new big opportunities to the whole crypto universe.