I tend to disagree with the fact that you made mention about Tottenham Hotspur doing fine under Mourinho, in my opinion much was expected from the Mourinho, but he seems not to be getting some things right, particularly the defense of Tottenham
Regarding to defense system and its power under management of Mourinho, I see you forgot a fact that with any team, their defense systems are positively or negatively (depends) affected by the power of their attack systems.
Attack components is the best way to defense. With some injuries on their stars (Kane, Son), their abilities to attack components decreased and their defense system has been under more pressure from their components. More conceded goals, consequently.
As regards Liverpool match, they will win West Ham, perhaps the margin might be by a goal or two perhaps more, Klopp might rest some key players against against West Ham today
Liverpool would want to finish their race to their first Premier League, after long waiting decades so they will put all their strength and human resources to the match. They will win it.