Although I have never had an issue of not being able to access my Bitcoin wallet holding any amount of Bitcoin, but I have had an issue of misplaced keys holding another assets. It wasn't a funny experience as I needed to trade the asset for fiat in order to solve a problem I had offline. I became increasingly devasted at every passing hour as I combed through all nooks and crannies of my house. It was a sorry stated for me that day. Till now I am yet to find the keys to that wallet. This is one very ugly side of cryptocurrencies. That experience taught me better ways to protect and keep my crypto assets safe and secured.