My recommendation is get a Ledger Nano S. It has support for most well known coins and tokens, is relatively cheap compared to some other vendors, and their newest model, the Nano X. Hardware wallets offer the best combination of security of funds and ease of use.

If you are looking for a Bitcoin-only wallet, you can also take a look at Electrum. It is a software wallet but it is the safest and best one available, and it doesn't need a full download and sync of the blockchain.
I can't comment on wallets for altcoins since you didn't mention what assets you are planning on storing in your wallet.