Speaking of Monero, it has been constantly improving its PoW algorithm every 6 months to maintain ASIC resistance. While this is good for mainstream adoption, it harms the security of the underlying blockchain network.
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This in turn, leads to a smaller hashrate on the network making it easy for anyone to attack the chain at will.
Speaking from a trading perspective, at one point of time in 2017 Monero was good to be considered as an alternative to Bitcoin in terms of anonymity and using the CryptoNote algorithm but practically speaking almost all the altcoins are losing its potential to withstand the market. There has been various de-listings of XMR from exchanges and there aren't hardly any news to support the stability for a longer run.
Though Bitcoin is harder to mine with the current difficulty they re-adjust based on the price actions. When a miner feels like he is no longer able to run into profits from his mining activity, they would be leaving the network for other miners and subsequently we would be seeing a drop in difficulty.
But ASIC resistant on the other hand could be a positive move from the XMR dev team to make the coin more decentralized. ASIC mining would make the coin community rely on a particular company to mine their coins thereby encouraging centralization. We should be very well aware of CZ trying to manipulate the whole network by hiring miners to reverse his binance loss from the hack. If a rich person tend to change the working of a currency to the way he likes, isn't considered to be unhealthy for the whole market and the coin?