Thanks again for the replies, you guys help is really appreciated!

I think something got mixed up here. I do only own ONE NewPac ASIC stick, not two. Maybe i was a bit unclear about that.

I tried uninstalling and reinstalling with computerrestarts after every step. -> same error as before
Also i tried to run cgminer on a different laptop (also win10) which gave the same error pattern.

Windows shows that the driver works correctly after installation using zadig.

Any other suggestions?