From 2099 till 2140 (when the last satoshis will be mined) there will only be one bitcoin mined. By the end of the century, supply is virtually fixed and limited to the maximum of 21 million. For the following forty years, miners will be mining only one bitcoin...
With all the transactions (and most tx fees) being forced onto second layers, it will be interesting to see how this affects the incentives of miners and their motivation to secure the blockchain.