It depend on the coin that you choose, if you just choose a masternode coin that doesn't have a potential you maybe end up in lose. I heard a good masternode coin and has given a high profit i.e dash coin. But you need to spend a lot of money to hold at least 1000 dash to start. Also when you choose a staking coin then I think ethereum is the best coin that  should you choose. Both of coin have good position in the market, at least you just need a little chance to experience a huge lose.