I didn't used coinbase pro, so I don't know if stop loss features available there. But those exchange support stop loss you may set it on there. There are some advantages & disadvantage of the stop loss. Advantage is, the stop loss would help you to prevent huge loss. The disadvantage is, you would miss profits due to stop loss if coin price start pump after hit stop loss. But personally I believe advantage is stronger than disadvantage. You may use stop loss to prevent huge loss of your total portfolio.