Bitcoin is the most talked about and top class security for transactions in the world today, where no third party has a hand and there is no chance of losing money.
Nope. As time goes by, there is an increasing cases of the lose of bitcoin not because of the removal of intermediary or by the protocol itself but rather with the mismanagement of people and businesses on their bitcoin and private keys.
Some of the incident worth mentioning here is the Mt.Gox fiasco where they lost an approximate $460 worth of bitcoin due to poor handling of private keys. Moreover, being ignorant and uneducated in the cryptospace could also lead to depressing unforeseen event.