I would personally never enter into transaction to take a loan in crypto currencies. I think that this would be extremely risky to do with such price volatility. And, with loan you need also to earn enough to pay interest and return borrowed money.
First of all, you need to know the intention you borrow the coin/crypto. I think if you just borrow the coin for your need in your real life it would be worst. But if you borrow the coin for trading purpose seem like it is a good idea as long as you believe that you can pay the loan on time and you get profit on it. I see some cases in this forum who borrow the coin (most of them use bitcoin) for trading purpose and so far it's a promising business IMO.