When we notice a movement of huge amounts then we assume there would happen manipulation. So probably that whales will manipulate something like Bitcoin or other altcoins. That kind of movement could shake the markets if it does to single coins. However, it would be transferred normal reason as well, who knows if the whales transferred funds to trade.

I think you have to research more about the difference between exchange and personal wallet. When fund transferred into exchanges means it's out of your control. Don't forget, your key, your bitcoin. Binance will never give your private key and your funds would freeze at any time for money Laundering.