As far as I know, clocks don't mess with warranty or lifespan of GPUs, the factors that can reduce lifespan are temperature and voltage, and I reduce both
The system is very stable with this clock
I don't fell confortable to do a bios mod with these cards, I didn't have any problems with polaris bios mod in the past, but with these 5700, I won't change for now
Did you try AMD Mem Tweak XL to reduce mvddc & mvddci? Does it work?