I think not yet because there's a lot of things that DEX cannot do right now compare to CEX. DeFi is having a great run this year but with lots of scams and hacks going on, people like me still prefer to use CEX for the safety of my investment.
Like seriously? CEX for safety of your investments? I think you are talking the opposite. Remember you are never in total control of your funds when it comes to centralized exchanges and CEX are prone to hacks, but for DEX like UNISWAP, your funds will be in your possession while you carry out swaps. Decentralized exchanges achieved huge milestones this year, the major propeller was Uniswap. Uniswap's large trading volumes and liquidity shows a lot of interest was drifted towards it, many other DEX which cloned Uniswap are fast rising even on other blockchains like TRON and BSC.