It is ok to do whether your for long term gains or quick gains. There's less stress in long term and opposite with the short term. Both are profits depending to the total amount you have invested.
But in short term, more pressure. And with the defi hype, there is a chance that they can also be scammed if they are for quick profits. Both has pros and cons.
When investing in altcoins for the long term it is like gambling because no one can guarantee a profit, whereas if investing in bitcoin is still a little possible to be profitable because bitcoin has a very strong influence from very high demand and very much supply, far different from the DeFi project, which may only be popular for a moment.