He will not do it, i don't remember any rematches that he agree to play with, and Mayweather will not let his guard down, he will not let other people win the game because they might do like what he did to them, if he will make a rematch with Manny expect that it will create a tons of money again, but the thing is he will not be the winner this time and I am sure of it, and if ever I will not bet in this game, I rather bet in not so well known boxer rather than a game with Floyd.
Mayweather will really hold into that record until he dies. I think it would be a miracle if Mayweather fights again Sen. Manny Pacquiao, if that is the case I find this rematch to be impossible. Maybe another rematch to McGregor is a match he would approve, because it would be another millions in his pocket. He's amazing to achieve an unbeatable run until he hang his gloves, we can't argue about that but accepting these matches might've hit some of the boxers that wanted to face him.
I don't really see why that will not happen as there is a lot of possibility that we need to consider especially the amount that Mayweather will accumulate either he win or he lose. Anyway, it might not only on Mayweather side that the match may not be held as Manny's wife and grandmother is too worried for him in matches with well-known boxer i.e. Mayweather.
Anyway, I can this rematch to happen before any of those two hang their gloves for good for their last match and I'll be watching it.
Probably the rematch will generate a bigger money than the first one, the first one was called as the fight of the century but in essence it's really not as it turns out a boring fight, more on running as Mayweather dictated the pace, maybe in the 2nd time Manny will be lucky then people will be satisfied.