It depends on the type and model of your vga and perhaps other components of your system. 
If your GPU has equal to or less than 4GB of memory, then your choice of coin to mine is limited. 
Example,  If you have an old GTX 750TI with only 2Gig of mem, then you could mine Aion with gminer..

For modern AMD   GPUs with > 4Gig of mem I would mine ETH using Team Red miner or Phoenixminer.
For modern nVidia GPUs with > 4Gig of mem I would mine ETH using T-Rex miner or Phoenixminer. 
There is also Nbminer and Bminer and more.