Topics pop up about this every day and I suggest you follow them.
Every day, multiple times a day in multiple sections. There's no need for this one TBH.
Not that I can predict which alts are going to give the best bang for the buck, I'm sticking with proof of stake coins in 2021 (and
BTC of course). I've always thought POS coins have been overlooked, and that's surprised me. They offer an opportunity to earn passive income, which is what everyone seems to want.
As for picks, I'm going with Neo, PIVX, Curecoin (because of the folding at home project), and Gridcoin (for the same reason). Can't really afford to own a lot of different coins right now, though there are some really good ones out there.