at op
No.1 most expensive part will be the GPUs. So take your time choosing. I would go with either RX 5600XT or 5700(XT) from AMD
or 3060TI / 3080 from the nVidia side.
No.2 is PSU. Buy 2x 750/ 850Watt PSUs instead of one single 1600W PSU. These things are expensive.
There are a lot of dedicated mining mobos to choose from. Or get an ASUS Prime mobo that has 6 pcie slots.
You can get Z270-Ps second hand.
Then there is a whole industry doing mining frames for GPU rigs. You could get a Veddha or a Banggood. Or design or build your own. Your choice.
You need risers. Any from version 006S and up are good.
Generally, prices have gone up a lot due to the all coin new moon season. Even 2nd hand parts.