For whatever reason you have to sell, having a strategy set up in advance is never a bad thing. Trying to match the top is far more difficult than predicting the bottom (e.g. 200W MA) in my opinion. For that reason, a sell ladder can be a good strategy. It's automatic and it won't cause you stress trying to match the exact top.

I personally sold some coins between $30-40k to reinvest in real-estate. I could have held them for longer for more fiat gains, but I had a strategy set up a long time ago and I held on to it. No regrets.

Right now I have no need for more fiat, so I have no further plans to sell anything.