As long as the reputation of Binance (exchanges) is good and still become the top exchanges of Centralized exchanges, Binance coin could replace Ethereum.
But we can't deny the fact if Centralized exhanges always have been targeted of hacker and each year there at least 1 exchanges will be hacked, Binance ever got hacked once on 2019.

So, be aware if Binance will get hacked in the future... the coin value will got affected too.