I use them at the newsstand by my office building in midtown Manhattan, to buy chewing gum and newspapers.  I use them to make charitable donations to a school in Chad and another in Kyrgyzstan.  I use them to pay rent on my apartment on the UES.  Eventually I should be able to replace most of my uses of fiat with uses of BTC.  I will generally shop at Overstock or TigerDirect when possible, avoiding Amazon until they take bitcoin.  For now, I still spend a lot on airlines, and generally use AmEx in restaurants, and still pay utilities with checks.  The experiment is working about as well as could reasonably be expected, for me.  Continued success seems probable.  A Bitcoin debit card would be huge for me.