Both are safe and you won't have problem with them. If you're worried about getting hacked, it's because of your negligence. Don't input your seeds to any forms online whether you use ledger nano s or trezor.

About PC having no anti virus, there's a chance you'll be hacked by those copy paste address attack. Otherwise, you're free and safe because these two are the most reputable. Btw, I own a Ledger Nano S and its still working.