To delete the profiles just do the following from the miner's UI:

Quick Actions, stop bosminer
System > Software, install luci-app-commands
System > Custom Commands
  Configure > Add
      Name: Delete profiles
      Command: rm /etc/bosminer-autotune.json
  Dashboard > Run Delete profiles
Quick Actions, start bosminer

Of course you could instead just ssh into the miner and do the same:
ssh root@IP_ADDRESS '/etc/init.d/bosminer stop && rm /etc/bosminer-autotune.json && /etc/init.d/bosminer start'

Or do it in batch using the bos-toolbox:
bos-toolbox command iplist.txt "/etc/init.d/bosminer stop && rm /etc/bosminer-autotune.json && /etc/init.d/bosminer start"

Isn't it great to have a proper OS running in your miner, rather than that Xilinx crud everyone else just modifies because they are too lazy to do any better?