Here are the Premier League games taking place on 4th April 2021:

Southampton vs Burnley

Newcastle United   vs Tottenham Hotspur

Aston Villa vs Fulham

Manchester United vs Brighton and Hove Albion



Here are my opinions on how the games will play out 

Southampton 1-2 Burnley
Newcastle United   1-3 Tottenham Hotspur
Aston Villa 2-1 Fulham
Manchester United 4-1 Brighton and Hove Albion