Of course but I've been given no reason why Mycelium can't handle this transaction and will calculate transaction fees properly? I have experience scanning a private cold storage wallet and sending it but the electrum thing is beyond me.
I can give you a suggestion.
Why don't you do everything with a low amount first? Then you will learn how to do it and will get some confidence before dealing with the real money.
Create a new paper wallet, with just one input. Send some funds to it (i can send you some dust if you need)
Then you try to open it in electrum wallet, just like you would do in your real funded wallet. You do all the steps you will have to do and send that amount to ledger nano.
You will be more confident before dealing with your real wallet.
You can also use Mycellium if you prefer, although I never used it and I don't trust it as I trust electrum.