Nvidia cards have always been pretty kind to me tuning wise.  I love my AMD cards, but they like to crash when pushed too far.  On a 1080 you'll want to tweak it manually as much as possible since the base hash rate is just OK.

Manually overclock it using afterburner starting with memory.  With phoenix miner running, just push the memory frequency up until you start to get artifacts or your hash rate drops, you can probably run the memory pretty close to a gaming overclock level.  Once that's maxed out lower the core freq until the hash rate starts to drop.  Once that's done just lower the power limit until you get a hash rate drop.  You might get some lag or glitchiness,  but like I said, Nvidia cards are usually pretty easy to tune this way.

Longer term you'll want to monitor for excess stale or incorrect shares, but unless you're on a 30 series card, the random incorrect/stale issues are pretty rare.