First am not a pro trader, but my trading techniques have proven fundamentals. I recycled around Bitcoin and some handful of good altcoins; I trade with a hand full of funds since altcoins and the bitcoin market move in the opposite direction; I fill my bags with altcoins when the alt markets are down against Bitcoin and sell them when the market is on the rise to buy bitcoin which will be on a downtrend at that moment.
That's what almost everyone does!
For me trading againts btc using only USDT is better then altcoin.
In my opinion, it doesn't matter which currency you are using to trade Bitcoin. The thing matters the most is where do you exchange the Bitcoin, there are some price difference between each exchange and you could potentially min-max it if you are really into it.