If you mean bluffing, then real poker player will not fall very often on that trick as long as there is strong base on the card statistics which they are analysing and practicing many times. I don't know what kind of strategy you are pertaining but being good on probability and statistics is the only strategy needed to win on poker. Bluffing is just an add-ons and will not gonna work against professional player.
It is true that probability and statistics are fundamental. But there are many variants and strategies. So it is necessary to be able to read the opponent, to try to understand what this strategy is. If you stick to the statistics, the chances of losing increase. We cannot forget that a human player can be unpredictable.