It would be a lot easier for customers if the site could just hold 1 currency, USD, EUR or even mbc. Using all kinds of different units opens up more questions than answers. on the other hand, it just depends on what the user is used to and what he feels good about.
I have opposite opinion on this matter. It is better to have a lot of options so they can reach a lot of users with varied preferences. Why would those different options raise more questions? Each alt or token listed, you can already see their min deposit/withdrawal, and what network you want to use, when you click each of them. It is better to have lots of options in my opinion.
Of course, it is better to have several options.
This is primarily due to what kind of deposit and in what currencies the player can enter the site. In some countries, commissions for top cryptocurrencies are completely unacceptable. Then they have a choice either to use a cryptocurrency with low commission rates and play, or simply refuse the services of this site. Here I think the choice is obvious. Of course, you have to have several options. They remembered here Tron, - here is one of the good examples.