With the accelerating pace of technological change, I believe soon it will be possible to run full nodes even on mobile devices. In the meantime, am pretty sure some solutions will be introduced to reduce the blockchain size or the time it takes to download it and synchronize with the network.
Will pruned nodes be their only option?
By running a pruned node you still need to download all the blocks. It only helps solving the storage issue as you will keep only the most recent blocks. Besides, we will still need others to run full nodes.