First of all, for the channel to be successful, Cyrus has to wear a bikini in a swimming pool on an big
banana (NSFW)

More seriously, I would be very interested in interviews or debates about Bitcoin or Bitcointalk.
I think it could have a better retention rate if it's live-streamed with a segment that guests take questions from the chat.
I quite agree with that. Interactivity is an important element.
In addition to what has been said, making small games/contests (price prediction, art contests, etc...) can be nice to win a small handful of BTC and/or why not a special badge (don't yell at me). As I'm evil, participants will have to post their answers on a dedicated topic on Bitcontalk (to avoid alts on YT and be at least a Jr Member or more to (almost) avoid alts on Bitcointalk).