No there have been too many changes for the 0.1.0 version to be compatible with the current bitcoin blockchain.

Running anything other than the latest version is kind of asking for getting vulnerabilities, I think there was a version a few years ago that had a few critical vulnerabilities that had to be patched (partly to do with DDoS and something else)...

I think there's a version around 8.8 or 12 that is compatible with the most recent blockchain, however, doesn't benefit from the lower transaction fees the newer software has that makes it able to segregate signatures away from the transaction making it quite a bit smaller. I also think the original version used a public key for identifying who funds were being sent to (making it much bigger than just using a hash of the key)

There have also been releases with the more recent versions to increase initial block download time and client synchronisation (since it's around 350GB now I think).