Yes but it's not really a gamble where you win, you win and when you lose, you lose. It's sort of an investment rather than gambling honestly, you will need capital to purchase some NFT then use the NFT to earn so the only lose here is when the price of the NFT crash unlike gambling there's 2 ways to lose, lose in gambling and when the price crash.
That's why before you buy an NFT item from the game, you need to do some prior assessment. I am seeing that some of the NFT characters are quite expensive from my standard and yet, they are gaining interest from the gaming community. It means, a lot of gamers are really willing to spend some cash on these NFT-based games. Which, if you will do good can really give you good returns even if we say you spend a lil bit of your savings. In some way, you are gambling here as you have no assurance if the game will survive long or not. But I believe, your chances of getting back your investments is relatively high, if in case you choose a strong gaming platform.