Those users probably know the risk they are facing or probably not, those users with big losses might not be a big losses to them. For me I think $1000 is a big losses for me but for gamblers with a balance of around $100,000 I don't think it's a huge loss.
Some gamblers really tried their luck in gambling probably because of quick money or because they want to win back their losses. I think the root of all of these were lack of knowledge and discipline.