Manchester City is strong enough without Kane. Don't judge them by the performance of just one match. In the Harry Kane team, they will actually be more stronger. However, Chelsea and Manchester United are the title contenders this season. Both teams seemed very stable. They do well enough. If Manchester City can't improve their performance quickly, they will gradually move away from the title.
Isn't it too early to think too negatively about Man City just because of one game ago? Team performance goes up and down isn't it normal? But the defeat must be a lesson for Man City to win the title again. It's not too late to achieve it, but the stability and strategy must change a lot.