Ouch! That will truly hurt and haunt the man till he passes on. One would've expected that with such huge quantity of coins, that our man would've taken extreme care to back up his private key in more than one places. However, good a thing that's not much Bitcoin. In terms of units with current price, that should be about 20btc perhaps. The sad happenstance here is that the victim (should I even call them that?) will feel more hurt anytime Bitcoin begins to moon again.
Honestly speaking, as little as 1 BTC may look it's still a big quantity to me..